Peter M Andersen Selected Research

Superoxide Dismutase-1

1/2022	SOD1 mutations associated with amyotrophic lateral sclerosis analysis of variant severity.
1/2021	Peripheral administration of SOD1 aggregates does not transmit pathogenic aggregation to the CNS of SOD1 transgenic mice.
1/2019	The molecular pathogenesis of superoxide dismutase 1-linked ALS is promoted by low oxygen tension.
12/2018	Mutant superoxide dismutase aggregates from human spinal cord transmit amyotrophic lateral sclerosis.
6/2017	Pyrimethamine significantly lowers cerebrospinal fluid Cu/Zn superoxide dismutase in amyotrophic lateral sclerosis patients with SOD1 mutations.
1/2016	Effects of Cellular Pathway Disturbances on Misfolded Superoxide Dismutase-1 in Fibroblasts Derived from ALS Patients.
1/2016	Two superoxide dismutase prion strains transmit amyotrophic lateral sclerosis-like disease.
4/2015	Structural and kinetic analysis of protein-aggregate strains in vivo using binary epitope mapping.
3/2013	Composition of soluble misfolded superoxide dismutase-1 in murine models of amyotrophic lateral sclerosis.
1/2013	Expression of wild-type human superoxide dismutase-1 in mice causes amyotrophic lateral sclerosis.

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Peter M Andersen Research Topics

Disease

76	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 11/2022 - 12/2002
10	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2022 - 12/2002
5	Motor Neuron Disease (Primary Lateral Sclerosis) 12/2014 - 06/2003
4	Parkinson Disease (Parkinson's Disease) 01/2022 - 12/2011
2	Frontotemporal Dementia (Semantic Dementia) 01/2022 - 10/2012
2	Spinal Muscular Atrophy (Progressive Muscular Atrophy) 01/2022 - 12/2021
2	Disease Progression 01/2022 - 03/2012
2	Asymptomatic Diseases 01/2022 - 01/2018
2	Respiratory Insufficiency (Respiratory Failure) 01/2020 - 03/2012
2	Hypoxia (Hypoxemia) 01/2017 - 10/2008
1	Alzheimer Disease (Alzheimer's Disease) 01/2022
1	Neuroinflammatory Diseases 11/2020
1	Embolism (Embolus) 01/2020
1	Leukocytosis (Pleocytosis) 01/2020
1	Melanoma (Melanoma, Malignant) 12/2019
1	Sarcoma (Soft Tissue Sarcoma) 01/2018
1	Charcot-Marie-Tooth Disease (Peroneal Muscular Atrophy) 01/2018
1	Paraplegia (Spastic Paraplegia) 01/2018
1	Polyneuropathies (Polyneuropathy) 01/2016
1	Dementia (Dementias) 01/2016
1	Atrophy 09/2012
1	Cerebellar Ataxia (Dysmetria) 01/2012
1	Nervous System Diseases (Neurological Disorders) 10/2008
1	Iron Overload 03/2008
1	Friedreich Ataxia (Friedreich's Ataxia) 03/2008
1	Myoglobinuria 03/2008
1	Muscular Diseases (Myopathy) 03/2008

Drug/Important Bio-Agent (IBA)

27	Superoxide Dismutase-1IBA 01/2022 - 06/2003
17	Proteins (Proteins, Gene)FDA Link 01/2021 - 07/2007
13	Superoxide DismutaseIBA 12/2018 - 12/2002
8	Biomarkers (Surrogate Marker)IBA 01/2022 - 08/2009
3	Superoxides (Superoxide)IBA 03/2013 - 12/2006
3	angiogeninIBA 12/2011 - 04/2006
3	ZincIBA 07/2007 - 12/2002
3	CopperIBA 07/2007 - 12/2002
2	tofersenIBA 01/2022 - 01/2020
2	Amyloid (Amyloid Fibrils)IBA 01/2022 - 01/2016
2	MicroRNAs (MicroRNA)IBA 01/2021 - 11/2014
2	PrionsIBA 01/2020 - 01/2016
2	KinesinsIBA 01/2018 - 10/2014
2	Myosin Heavy Chains (Myosin Heavy Chain)IBA 01/2017 - 07/2010
2	Chromogranin BIBA 11/2016 - 12/2009
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 10/2008 - 08/2003
1	Biological ProductsIBA 10/2022
1	TransketolaseIBA 12/2021
1	Oxidoreductases (Dehydrogenase)IBA 12/2021
1	Immunoglobulin A (IgA)IBA 11/2020
1	Cathepsin DIBA 12/2019
1	IgA receptor (protein B)IBA 12/2019
1	Glycoproteins (Glycoprotein)IBA 12/2019
1	Peptides (Polypeptides)IBA 12/2019
1	Ubiquitin Thiolesterase (Ubiquitin Carboxy-Terminal Hydrolase)IBA 12/2019
1	Heat-Shock Proteins (Heat-Shock Protein)IBA 01/2018
1	NucleotidesIBA 01/2018
1	arimoclomolIBA 01/2018
1	Pyrimethamine (Daraprim)FDA Link 06/2017
1	Pharmaceutical PreparationsIBA 01/2017
1	Metalloproteases (Metalloproteinases)IBA 01/2016
1	Neprilysin (Neutral Endopeptidase)IBA 01/2016
1	MMEIBA 01/2016
1	Codon (Codons)IBA 12/2014
1	CholesterolIBA 01/2014
1	DNA-Binding Proteins (DNA Binding Protein)IBA 09/2012
1	Levodopa (L Dopa)FDA LinkGeneric 01/2012
1	polyglutamineIBA 01/2012
1	Ataxin-2IBA 01/2012
1	Laminin (Merosin)IBA 07/2011
1	Protein Isoforms (Isoforms)IBA 07/2011
1	Glycine (Aminoacetic Acid)FDA LinkGeneric 10/2010
1	Amino Acids FDA Link 10/2010
1	Arginine (L-Arginine)FDA Link 10/2010
1	ChromograninsIBA 12/2009
1	ProteomeIBA 06/2009
1	ApolipoproteinsIBA 10/2008
1	Apolipoproteins E (ApoE)IBA 10/2008
1	IronIBA 03/2008
1	FrataxinIBA 03/2008
1	SulfurIBA 03/2008
1	Succinate Dehydrogenase (Fumarate Reductase)IBA 03/2008
1	sulofenur (ISCU)IBA 03/2008
1	Aconitate Hydratase (Aconitase)IBA 03/2008
1	Messenger RNA (mRNA)IBA 03/2008
1	Iron-Regulatory Proteins (Iron-Responsive Element Binding Proteins)IBA 03/2008
1	Flumazenil (Romazicon)FDA LinkGeneric 08/2007
1	EnzymesIBA 07/2005
1	Ciliary Neurotrophic Factor (CNTF)IBA 07/2003

Therapy/Procedure

4	Therapeutics 11/2022 - 01/2021
2	Gastrostomy 01/2017 - 03/2012
1	Noninvasive Ventilation 01/2017
1	Assisted Suicide (Physician Assisted Suicide) 01/2017